1n4h
From Proteopedia
(Difference between revisions)
m (Protected "1n4h" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1n4h.png|left|200px]] | ||
| - | |||
{{STRUCTURE_1n4h| PDB=1n4h | SCENE= }} | {{STRUCTURE_1n4h| PDB=1n4h | SCENE= }} | ||
| - | |||
===Characterization of ligands for the orphan nuclear receptor RORbeta=== | ===Characterization of ligands for the orphan nuclear receptor RORbeta=== | ||
| + | {{ABSTRACT_PUBMED_12958591}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/RORB_RAT RORB_RAT]] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter. | ||
==About this Structure== | ==About this Structure== | ||
| Line 11: | Line 10: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012958591</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012958591</ref><references group="xtra"/><references/> |
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Dorsselaer, A Van.]] | [[Category: Dorsselaer, A Van.]] | ||
Revision as of 19:38, 24 March 2013
Contents |
Characterization of ligands for the orphan nuclear receptor RORbeta
Template:ABSTRACT PUBMED 12958591
Function
[RORB_RAT] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
About this Structure
1n4h is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Stehlin-Gaon C, Willmann D, Zeyer D, Sanglier S, Van Dorsselaer A, Renaud JP, Moras D, Schule R. All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. Nat Struct Biol. 2003 Oct;10(10):820-5. Epub 2003 Sep 7. PMID:12958591 doi:http://dx.doi.org/10.1038/nsb979
