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2wq9
From Proteopedia
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| - | [[Image:2wq9.png|left|200px]] | ||
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{{STRUCTURE_2wq9| PDB=2wq9 | SCENE= }} | {{STRUCTURE_2wq9| PDB=2wq9 | SCENE= }} | ||
| + | ===CRYSTAL STRUCTURE OF RBP4 BOUND TO OLEIC ACID=== | ||
| - | === | + | ==Disease== |
| + | [[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[http://omim.org/entry/180250 180250]]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 19:49, 24 March 2013
Contents |
CRYSTAL STRUCTURE OF RBP4 BOUND TO OLEIC ACID
Disease
[RET4_HUMAN] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Function
[RET4_HUMAN] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
About this Structure
2wq9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
