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Template:STRUCTURE 2fkl

From Proteopedia

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Current revision

2fkl, resolution 2.50Å ()

Gene:

APP (Homo sapiens)

Related:

1owt, 2fjz, 2fk1, 2fk2, 2fk3

Structural annotation:
Resources:	InterPro : Ipr008154, Ipr013803, Ipr015849, Ipr011178, Ipr002223, Ipr008155 Pfam : PF02177 UniProt : P05067

Functional annotation:
Cellular component:	coated pit extracellular region integral to plasma membrane integral to membrane membrane cell surface
Biological process:	cell adhesion neuromuscular process apoptosis cellular copper ion homeostasis endocytosis Notch signaling pathway
Molecular function:	endopeptidase inhibitor activity identical protein binding binding protein binding serine-type endopeptidase inhibitor activity zinc ion binding heparin binding metal ion binding iron ion binding copper ion binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_2fkl"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2fkl, resolution 2.50&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2fkl]], [[Resolution|resolution]] 2.50&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |GENE= APP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00006 A4_EXTRA]</span>
 |RELATEDENTRY=[[1owt|1owt]], [[2fjz|2fjz]], [[2fk1|2fk1]], [[2fk2|2fk2]], [[2fk3|2fk3]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkl OCA], [http://www.ebi.ac.uk/pdbsum/2fkl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fkl RCSB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fkl RCSB], [http://www.ebi.ac.uk/pdbsum/2fkl PDBsum]</span>
 |FUNCTION={{GO|id=GO:0004866 | text = endopeptidase inhibitor activity}}{{GO|id=GO:0042802 | text = identical protein binding}}{{GO|id=GO:0005488 | text = binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0004867 | text = serine-type endopeptidase inhibitor activity}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0008201 | text = heparin binding}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005506 | text = iron ion binding}}{{GO|id=GO:0005507 | text = copper ion binding}}
 |PROCESS={{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0050905 | text = neuromuscular process}}{{GO|id=GO:0006915 | text = apoptosis}}{{GO|id=GO:0006878 | text = cellular copper ion homeostasis}}{{GO|id=GO:0006897 | text = endocytosis}}{{GO|id=GO:0007219 | text = Notch signaling pathway}}
 |COMPONENT={{GO|id=GO:0005905 | text = coated pit}}{{GO|id=GO:0005576 | text = extracellular region}}{{GO|id=GO:0005887 | text = integral to plasma membrane}}{{GO|id=GO:0016021 | text = integral to membrane}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0009986 | text = cell surface}}
 |SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008154 Ipr008154], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013803 Ipr013803], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR015849 Ipr015849], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011178 Ipr011178], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002223 Ipr002223], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008155 Ipr008155]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF02177 PF02177]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P05067 P05067]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P05067 P05067]</span>
+|uPDB=2FKL|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_2fkl_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_2fkl_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 2fkl

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