Template:STRUCTURE 1uwh

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1uwh]], resolution 2.95&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1uwh]], [[Resolution|resolution]] 2.95&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+B'>AC1</scene>
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|LIGAND= <scene name='pdbligand=BAX:4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE'>BAX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
|LIGAND= <scene name='pdbligand=BAX:4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE'>BAX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span>
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|RELATEDENTRY=[[1uwj|1uwj]]
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00220 S_TKc], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00180 S_TKc]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uwh RCSB], [http://www.ebi.ac.uk/pdbsum/1uwh PDBsum]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwh OCA], [http://www.ebi.ac.uk/pdbsum/1uwh PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1uwh RCSB]</span>
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|FUNCTION={{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0004674 | text = protein serine/threonine kinase activity}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0005057 | text = receptor signaling protein activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0019992 | text = diacylglycerol binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}
|FUNCTION={{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0004674 | text = protein serine/threonine kinase activity}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0005057 | text = receptor signaling protein activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0019992 | text = diacylglycerol binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}
|PROCESS={{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0006916 | text = anti-apoptosis}}{{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0009887 | text = organ morphogenesis}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}
|PROCESS={{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0006916 | text = anti-apoptosis}}{{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0009887 | text = organ morphogenesis}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}
|COMPONENT={{GO|id=GO:0005886 | text = plasma membrane}}{{GO|id=GO:0005737 | text = cytoplasm}}
|COMPONENT={{GO|id=GO:0005886 | text = plasma membrane}}{{GO|id=GO:0005737 | text = cytoplasm}}
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhA02 1Uwha02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhA01 1Uwha01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhB02 1Uwhb02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhB01 1Uwhb01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003116 Ipr003116], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000719 Ipr000719], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008271 Ipr008271], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002219 Ipr002219], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011009 Ipr011009]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00069 PF00069]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=100123 d1uwha_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=100124 d1uwhb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P15056 P15056]</span>
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhA02 1Uwha02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhA01 1Uwha01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhB02 1Uwhb02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1uwhB01 1Uwhb01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003116 Ipr003116], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000719 Ipr000719], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008271 Ipr008271], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002219 Ipr002219], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011009 Ipr011009]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00069 PF00069]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=100123 d1uwha_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=100124 d1uwhb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P15056 P15056]</span>
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=BRAF BRAF]</span>
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|uPDB=1UWH|CONSURF={{!}}-
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|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Current revision

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1uwh, resolution 2.95Å ()
Ligands: ,
Related: 1uwj
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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