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Template:STRUCTURE 1a36

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Current revision

1a36, resolution 2.80Å ()

Activity:

DNA topoisomerase, with EC number 5.99.1.2

Structural annotation:
Resources:	CATH : 1A36A03, 1A36A02, 1A36A01, 1A36A04 InterPro : Ipr011010, Ipr009054, Ipr013500, Ipr013499, Ipr001631, Ipr013030, Ipr008336, Ipr014727, Ipr014711 Pfam : PF02919, PF01028 SCOP : d1a36a2, d1a36a1, d1a36a3 UniProt : P11387

Functional annotation:
Cellular component:	nucleolus perikaryon chromosome nucleoplasm cytoplasm nucleus
Biological process:	DNA unwinding during replication response to drug embryonic cleavage phosphorylation DNA topological change programmed cell death DNA replication
Molecular function:	DNA topoisomerase activity DNA topoisomerase (ATP-hydrolyzing) activity DNA binding chromatin binding protein binding isomerase activity DNA topoisomerase type I activity

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1a36"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1a36, resolution 2.800&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1a36]], [[Resolution|resolution]] 2.80&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] </span>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00659 Topo_IB_C], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03488 Topoisomer_IB_N_htopoI_like], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3569 COG3569]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a36 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a36 RCSB], [http://www.ebi.ac.uk/pdbsum/1a36 PDBsum]</span>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a36 OCA], [http://www.ebi.ac.uk/pdbsum/1a36 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a36 RCSB]</span>
 |FUNCTION={{GO|id=GO:0003916 | text = DNA topoisomerase activity}}{{GO|id=GO:0003918 | text = DNA topoisomerase (ATP-hydrolyzing) activity}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0003682 | text = chromatin binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0016853 | text = isomerase activity}}{{GO|id=GO:0003917 | text = DNA topoisomerase type I activity}}
 |PROCESS={{GO|id=GO:0006268 | text = DNA unwinding during replication}}{{GO|id=GO:0042493 | text = response to drug}}{{GO|id=GO:0040016 | text = embryonic cleavage}}{{GO|id=GO:0016310 | text = phosphorylation}}{{GO|id=GO:0006265 | text = DNA topological change}}{{GO|id=GO:0012501 | text = programmed cell death}}{{GO|id=GO:0006260 | text = DNA replication}}
 |COMPONENT={{GO|id=GO:0005730 | text = nucleolus}}{{GO|id=GO:0043204 | text = perikaryon}}{{GO|id=GO:0005694 | text = chromosome}}{{GO|id=GO:0005654 | text = nucleoplasm}}{{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0005634 | text = nucleus}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1a36A03 1A36A03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1a36A02 1A36A02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1a36A01 1A36A01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1a36A04 1A36A04]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011010 Ipr011010], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009054 Ipr009054], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013500 Ipr013500], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013499 Ipr013499], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001631 Ipr001631], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013030 Ipr013030], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008336 Ipr008336], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014727 Ipr014727], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014711 Ipr014711]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF02919 PF02919], [http://pfam.sanger.ac.uk/family?acc=PF01028 PF01028]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=42173 d1a36a2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=15715 d1a36a1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=43266 d1a36a3]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P11387 P11387]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=TOP1 TOP1]</span>
+|uPDB=1A36|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_1a36_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>C [x]</text>
+<name>jmb_1a36_C</name>
+<title>toggle chain C</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1a36_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1a36

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