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4e52
From Proteopedia
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| - | + | {{STRUCTURE_4e52| PDB=4e52 | SCENE= }} | |
| + | ===Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D=== | ||
| + | {{ABSTRACT_PUBMED_19799916}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN]] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. | ||
| - | + | ==About this Structure== | |
| + | [[4e52]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E52 OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:019799916</ref><ref group="xtra">PMID:012888356</ref><references group="xtra"/><references/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Greenhough, T J.]] | ||
| + | [[Category: Shrive, A K.]] | ||
| + | [[Category: Alpha-helical coiled coil]] | ||
| + | [[Category: Carbohydrate recognition domain]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Neck+crd]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: Trimeric recombinant collectin fragment]] | ||
Revision as of 08:57, 27 March 2013
Contents |
Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D
Template:ABSTRACT PUBMED 19799916
Function
[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
About this Structure
4e52 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Shrive AK, Martin C, Burns I, Paterson JM, Martin JD, Townsend JP, Waters P, Clark HW, Kishore U, Reid KB, Greenhough TJ. Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325. J Mol Biol. 2009 Dec 11;394(4):776-88. Epub 2009 Sep 30. PMID:19799916 doi:10.1016/j.jmb.2009.09.057
- Shrive AK, Tharia HA, Strong P, Kishore U, Burns I, Rizkallah PJ, Reid KB, Greenhough TJ. High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D. J Mol Biol. 2003 Aug 8;331(2):509-23. PMID:12888356
