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3iqe

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Template:STRUCTURE 3iqe

Contents

Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methylene-tetrahydromethanopterin and coenzyme F420

Template:ABSTRACT PUBMED 19761261

Function

[MTD_METKA] Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.[1]

About this Structure

3iqe is a 6 chain structure with sequence from Methanopyrus kandleri. Full crystallographic information is available from OCA.

Reference

  • Ceh K, Demmer U, Warkentin E, Moll J, Thauer RK, Shima S, Ermler U. Structural Basis of the Hydride Transfer Mechanism in F(420)-Dependent Methylenetetrahydromethanopterin Dehydrogenase. Biochemistry. 2009 Sep 29. PMID:19761261 doi:10.1021/bi901104d
  1. ↑ Klein AR, Thauer RK. Overexpression of the coenzyme-F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase gene from the hyperthermophilic Methanopyrus kandleri. Eur J Biochem. 1997 Apr 15;245(2):386-91. PMID:9151968

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OCA

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