This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3jv3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3jv3" [edit=sysop:move=sysop])

Revision as of 09:15, 27 March 2013

Template:STRUCTURE 3jv3

Contents

Structure of SH3E-DH unit of murine intersectin-1L

Template:ABSTRACT PUBMED 20585582

Function

[ITSN1_MOUSE] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Inhibits ARHGAP31 activity toward RAC1.

About this Structure

3jv3 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Ahmad KF, Lim WA. The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin. PLoS One. 2010 Jun 24;5(6):e11291. PMID:20585582 doi:10.1371/journal.pone.0011291

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3jv3"
Personal tools