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3it4
From Proteopedia
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{{STRUCTURE_3it4| PDB=3it4 | SCENE= }} | {{STRUCTURE_3it4| PDB=3it4 | SCENE= }} | ||
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===The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A=== | ===The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A=== | ||
| + | {{ABSTRACT_PUBMED_20184895}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/ARGJ_MYCTU ARGJ_MYCTU]] Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity).[HAMAP-Rule:MF_01106] | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3it4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT4 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020184895</ref><references group="xtra"/><references/> |
[[Category: Glutamate N-acetyltransferase]] | [[Category: Glutamate N-acetyltransferase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
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[[Category: Amino-acid biosynthesis]] | [[Category: Amino-acid biosynthesis]] | ||
[[Category: Arginine biosynthesis]] | [[Category: Arginine biosynthesis]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Multifunctional enzyme]] | [[Category: Multifunctional enzyme]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
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[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:08:38 2010'' | ||
Revision as of 09:23, 27 March 2013
Contents |
The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A
Template:ABSTRACT PUBMED 20184895
Function
[ARGJ_MYCTU] Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity).[HAMAP-Rule:MF_01106]
About this Structure
3it4 is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sankaranarayanan R, Cherney MM, Garen C, Garen G, Niu C, Yuan M, James MN. The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor. J Mol Biol. 2010 Apr 9;397(4):979-90. Epub 2010 Feb 22. PMID:20184895 doi:10.1016/j.jmb.2010.02.018
Categories: Glutamate N-acetyltransferase | Mycobacterium tuberculosis | Cherney, M M. | Garen, C. | Garen, G. | James, M N. | Sankaranarayanan, R. | TBSGC, TB Structural Genomics Consortium. | Yuan, M. | Acyltransferase | Amino-acid biosynthesis | Arginine biosynthesis | Multifunctional enzyme | Ornithine acetyltransferase | Structural genomic | Transferase
