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3ke1
From Proteopedia
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Revision as of 02:18, 4 April 2013
Contents |
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with a fragment-nucleoside fusion D000161829
Function
[ISPF_BURPS] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
About this Structure
3ke1 is a 3 chain structure with sequence from Burkholderia pseudomallei. Full crystallographic information is available from OCA.
See Also
Categories: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Burkholderia pseudomallei | SSGCID, Seattle Structural Genomics Center for Infectious Disease. | D000161829 | Fbdd | Fragment crystallography | Fragment-based drug-design | Isoprene biosynthesis | Lyase | Metal-binding | Niaid | Nucleoside analog | Seattle structural genomics center for infectious disease | Ssgcid
