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3km8
From Proteopedia
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===Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine=== | ===Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/ADA_MOUSE ADA_MOUSE]] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3km8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA]. | |
[[Category: Adenosine deaminase]] | [[Category: Adenosine deaminase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Nucleotide metabolism]] | [[Category: Nucleotide metabolism]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 20 06:36:10 2010'' | ||
Revision as of 02:34, 4 April 2013
Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine
Function
[ADA_MOUSE] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity).
About this Structure
3km8 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
