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3k88

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[[Image:3k88.png|left|200px]]
 
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{{STRUCTURE_3k88| PDB=3k88 | SCENE= }}
{{STRUCTURE_3k88| PDB=3k88 | SCENE= }}
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===Crystal structure of NADH:FAD oxidoreductase (TftC) - FAD, NADH complex===
===Crystal structure of NADH:FAD oxidoreductase (TftC) - FAD, NADH complex===
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{{ABSTRACT_PUBMED_19915006}}
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==Function==
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[[http://www.uniprot.org/uniprot/O87008_BURCE O87008_BURCE]] Reductase component of a two-component system that degrades 2,4,5-trichlorophenol. TftC provides the FADH(2) required by TftD. TftD oxidizes 2,4,5-trichlorophenol (2,4,5-TCP) to 2,5-dichloro-p-benzoquinone, which is chemically reduced to 2,5-dichloro-p-hydroquinone (2,5-DiCHQ). Then, TftD oxidizes the latter to 5-chloro-2-hydroxy-p-benzoquinone.<ref>PMID:12700257</ref> <ref>PMID:19915006</ref>
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{{ABSTRACT_PUBMED_19915006}}
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==About this Structure==
==About this Structure==
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3K88 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K88 OCA].
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[[3k88]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K88 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19915006</ref><references group="xtra"/>
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<ref group="xtra">PMID:019915006</ref><references group="xtra"/><references/>
[[Category: Burkholderia cepacia]]
[[Category: Burkholderia cepacia]]
[[Category: Kang, C.]]
[[Category: Kang, C.]]
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[[Category: Nadh:fad oxidoreductase]]
[[Category: Nadh:fad oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 14:23:48 2010''
 

Revision as of 02:42, 4 April 2013

Template:STRUCTURE 3k88

Contents

Crystal structure of NADH:FAD oxidoreductase (TftC) - FAD, NADH complex

Template:ABSTRACT PUBMED 19915006

Function

[O87008_BURCE] Reductase component of a two-component system that degrades 2,4,5-trichlorophenol. TftC provides the FADH(2) required by TftD. TftD oxidizes 2,4,5-trichlorophenol (2,4,5-TCP) to 2,5-dichloro-p-benzoquinone, which is chemically reduced to 2,5-dichloro-p-hydroquinone (2,5-DiCHQ). Then, TftD oxidizes the latter to 5-chloro-2-hydroxy-p-benzoquinone.[1] [2]

About this Structure

3k88 is a 2 chain structure with sequence from Burkholderia cepacia. Full crystallographic information is available from OCA.

Reference

  • Webb BN, Ballinger JW, Kim E, Belchik SM, Lam KS, Youn B, Nissen MS, Xun L, Kang C. Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100. J Biol Chem. 2010 Jan 15;285(3):2014-27. Epub 2009 Nov 13. PMID:19915006 doi:10.1074/jbc.M109.056135
  1. ↑ Gisi MR, Xun L. Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:flavin adenine dinucleotide oxidoreductase (TftC) of Burkholderia cepacia AC1100. J Bacteriol. 2003 May;185(9):2786-92. PMID:12700257
  2. ↑ Webb BN, Ballinger JW, Kim E, Belchik SM, Lam KS, Youn B, Nissen MS, Xun L, Kang C. Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100. J Biol Chem. 2010 Jan 15;285(3):2014-27. Epub 2009 Nov 13. PMID:19915006 doi:10.1074/jbc.M109.056135

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