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3m1h
From Proteopedia
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{{STRUCTURE_3m1h| PDB=3m1h | SCENE= }} | {{STRUCTURE_3m1h| PDB=3m1h | SCENE= }} | ||
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===Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83=== | ===Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83=== | ||
| + | {{ABSTRACT_PUBMED_021812842}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/O52050_PORGI O52050_PORGI]] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Hunter, N.]] | [[Category: Hunter, N.]] | ||
[[Category: Li, N.]] | [[Category: Li, N.]] | ||
| + | [[Category: Beta jelly roll barrel]] | ||
| + | [[Category: Carbohydrate binding]] | ||
| + | [[Category: Cell invasion]] | ||
| + | [[Category: Cleaved adhesin family]] | ||
| + | [[Category: Hemagglutination domain]] | ||
| + | [[Category: Lys-gingipain]] | ||
| + | [[Category: Protease]] | ||
Revision as of 23:10, 10 April 2013
Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83
Template:ABSTRACT PUBMED 021812842
Function
[O52050_PORGI] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2]
About this Structure
3m1h is a 4 chain structure with sequence from Porphyromonas gingivalis. Full crystallographic information is available from OCA.
