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3lyr

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{{Seed}}
 
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[[Image:3lyr.png|left|200px]]
 
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{{STRUCTURE_3lyr| PDB=3lyr | SCENE= }}
{{STRUCTURE_3lyr| PDB=3lyr | SCENE= }}
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===Human Early B-cell Factor 1 (EBF1) DNA-binding domain===
===Human Early B-cell Factor 1 (EBF1) DNA-binding domain===
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{{ABSTRACT_PUBMED_20592035}}
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==Function==
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[[http://www.uniprot.org/uniprot/COE1_HUMAN COE1_HUMAN]] Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).
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{{ABSTRACT_PUBMED_20592035}}
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==About this Structure==
==About this Structure==
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3LYR is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LYR OCA].
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[[3lyr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LYR OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20592035</ref><references group="xtra"/>
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<ref group="xtra">PMID:020592035</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H.]]
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[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 15:58:20 2010''
 

Revision as of 23:17, 10 April 2013

Template:STRUCTURE 3lyr

Contents

Human Early B-cell Factor 1 (EBF1) DNA-binding domain

Template:ABSTRACT PUBMED 20592035

Function

[COE1_HUMAN] Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).

About this Structure

3lyr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Siponen MI, Wisniewska M, Lehtio L, Johansson I, Svensson L, Raszewski G, Nilsson L, Sigvardsson M, Berglund H. Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif. J Biol Chem. 2010 Aug 20;285(34):25875-9. Epub 2010 Jun 30. PMID:20592035 doi:10.1074/jbc.C110.150482

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