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2m0s

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[[Image:2m0s.jpg|left|200px]]
 
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{{STRUCTURE_2m0s| PDB=2m0s | SCENE= }}
{{STRUCTURE_2m0s| PDB=2m0s | SCENE= }}
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===Solution Structure of the trans-membrane domain of the NS2A of dengue virus===
===Solution Structure of the trans-membrane domain of the NS2A of dengue virus===
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{{ABSTRACT_PUBMED_23408612}}
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{{ABSTRACT_PUBMED_23408612}}
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==Function==
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[[http://www.uniprot.org/uniprot/Q9YKL3_9FLAV Q9YKL3_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]
==About this Structure==
==About this Structure==

Revision as of 10:21, 24 April 2013

Template:STRUCTURE 2m0s

Solution Structure of the trans-membrane domain of the NS2A of dengue virus

Template:ABSTRACT PUBMED 23408612

Function

[Q9YKL3_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]

About this Structure

2m0s is a 1 chain structure. Full experimental information is available from OCA.

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