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3o4r
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m (Protected "3o4r" [edit=sysop:move=sysop]) |
Revision as of 11:51, 24 April 2013
Crystal Structure of Human Dehydrogenase/Reductase (SDR family) member 4 (DHRS4)
Function
[DHRS4_HUMAN] Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).
About this Structure
3o4r is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Arrowsmith, C H. | Bhatia, C. | Bountra, C. | Delft, F von. | Edwards, A. | Krojer, T. | Oppermann, U. | SGC, Structural Genomics Consortium. | Ugochukwu, E. | Vollmar, M. | Weigelt, J. | Yue, W W. | Dehydrogenase/reductase | Oxidoreductase | Sgc | Structural genomic | Structural genomics consortium
