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3nfq
From Proteopedia
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{{STRUCTURE_3nfq| PDB=3nfq | SCENE= }} | {{STRUCTURE_3nfq| PDB=3nfq | SCENE= }} | ||
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===Crystal structure of the conserved central domain of yeast Spn1/Iws1=== | ===Crystal structure of the conserved central domain of yeast Spn1/Iws1=== | ||
| + | {{ABSTRACT_PUBMED_20875428}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/IWS1_YEAST IWS1_YEAST]] Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.<ref>PMID:12524336</ref> <ref>PMID:12556496</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3nfq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFQ OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020875428</ref><references group="xtra"/><references/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Luger, K.]] | [[Category: Luger, K.]] | ||
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[[Category: Spn1]] | [[Category: Spn1]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
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Revision as of 12:06, 24 April 2013
Contents |
Crystal structure of the conserved central domain of yeast Spn1/Iws1
Template:ABSTRACT PUBMED 20875428
Function
[IWS1_YEAST] Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.[1] [2]
About this Structure
3nfq is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Pujari V, Radebaugh CA, Chodaparambil JV, Muthurajan UM, Almeida AR, Fischbeck JA, Luger K, Stargell LA. The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif. J Mol Biol. 2010 Sep 25. PMID:20875428 doi:10.1016/j.jmb.2010.09.040
- ↑ Fischbeck JA, Kraemer SM, Stargell LA. SPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutant. Genetics. 2002 Dec;162(4):1605-16. PMID:12524336
- ↑ Lindstrom DL, Squazzo SL, Muster N, Burckin TA, Wachter KC, Emigh CA, McCleery JA, Yates JR 3rd, Hartzog GA. Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol. 2003 Feb;23(4):1368-78. PMID:12556496
