This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ngx
From Proteopedia
m (Protected "3ngx" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:3ngx.jpg|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3ngx", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3ngx| PDB=3ngx | SCENE= }} | {{STRUCTURE_3ngx| PDB=3ngx | SCENE= }} | ||
| - | |||
===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum=== | ===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum=== | ||
| + | {{ABSTRACT_PUBMED_21333632}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/FOLD_THEAC FOLD_THEAC]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity). | |
| - | + | ||
| - | + | ||
| - | -- | + | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| Line 22: | Line 10: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021333632</ref><references group="xtra"/><references/> |
[[Category: Thermoplasma acidophilum]] | [[Category: Thermoplasma acidophilum]] | ||
[[Category: Hwang, K W.]] | [[Category: Hwang, K W.]] | ||
[[Category: Lee, W H.]] | [[Category: Lee, W H.]] | ||
[[Category: Sung, M W.]] | [[Category: Sung, M W.]] | ||
| + | [[Category: 10-methenyltetrahydrofolate]] | ||
| + | [[Category: 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate]] | ||
| + | [[Category: 10-methylenetetrahydrofolate to 5]] | ||
| + | [[Category: Catalyzes the oxidation of 5]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Methylenetetrahydrofolate dehydrogenase/cyclohydrolase]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: The hydrolysis of 5]] | ||
Revision as of 12:07, 24 April 2013
Contents |
Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum
Template:ABSTRACT PUBMED 21333632
Function
[FOLD_THEAC] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).
About this Structure
3ngx is a 2 chain structure with sequence from Thermoplasma acidophilum. Full crystallographic information is available from OCA.
Reference
- Lee WH, Sung MW, Kim JH, Kim YK, Han A, Hwang KY. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Biochem Biophys Res Commun. 2011 Mar 18;406(3):459-63. Epub 2011 Feb 17. PMID:21333632 doi:10.1016/j.bbrc.2011.02.074
Categories: Thermoplasma acidophilum | Hwang, K W. | Lee, W H. | Sung, M W. | 10-methenyltetrahydrofolate | 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate | 10-methylenetetrahydrofolate to 5 | Catalyzes the oxidation of 5 | Hydrolase | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase | Oxidoreductase | The hydrolysis of 5
