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3opt
From Proteopedia
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{{STRUCTURE_3opt| PDB=3opt | SCENE= }} | {{STRUCTURE_3opt| PDB=3opt | SCENE= }} | ||
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===Crystal structure of the Rph1 catalytic core with a-ketoglutarate=== | ===Crystal structure of the Rph1 catalytic core with a-ketoglutarate=== | ||
| + | {{ABSTRACT_PUBMED_21067515}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/RPH1_YEAST RPH1_YEAST]] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.<ref>PMID:10523651</ref> <ref>PMID:11809875</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3opt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021067515</ref><references group="xtra"/><references/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Chang, Y.]] | [[Category: Chang, Y.]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Rph1]] | [[Category: Rph1]] | ||
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Revision as of 08:12, 2 May 2013
Contents |
Crystal structure of the Rph1 catalytic core with a-ketoglutarate
Template:ABSTRACT PUBMED 21067515
Function
[RPH1_YEAST] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.[1] [2]
About this Structure
3opt is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Chang Y, Wu J, Tong XJ, Zhou JQ, Ding J. Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism. Biochem J. 2010 Nov 10. PMID:21067515 doi:10.1042/BJ20101418
- ↑ Jang YK, Wang L, Sancar GB. RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol Cell Biol. 1999 Nov;19(11):7630-8. PMID:10523651
- ↑ Kim EM, Jang YK, Park SD. Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res. 2002 Feb 1;30(3):643-8. PMID:11809875
