This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ote

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3ote.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_3ote", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_3ote| PDB=3ote | SCENE= }}
{{STRUCTURE_3ote| PDB=3ote | SCENE= }}
- 
===Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I===
===Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I===
 +
{{ABSTRACT_PUBMED_21059936}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN]] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21059936}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21059936 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21059936}}
+
==About this Structure==
==About this Structure==
-
3OTE is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTE OCA].
+
[[3ote]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTE OCA].
==Reference==
==Reference==
-
<ref group="xtra">PMID:21059936</ref><references group="xtra"/>
+
<ref group="xtra">PMID:021059936</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Doublie, S.]]
[[Category: Doublie, S.]]
Line 32: Line 19:
[[Category: Polymerase-like palm domain]]
[[Category: Polymerase-like palm domain]]
[[Category: Transferase]]
[[Category: Transferase]]
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:21:55 2010''
 

Revision as of 08:23, 2 May 2013

Template:STRUCTURE 3ote

Contents

Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I

Template:ABSTRACT PUBMED 21059936

Function

[THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.[1]

About this Structure

3ote is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hyde SJ, Eckenroth BE, Smith BA, Eberley WA, Heintz NH, Jackman JE, Doublie S. tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc Natl Acad Sci U S A. 2010 Nov 8. PMID:21059936 doi:10.1073/pnas.1010436107
  1. Hyde SJ, Eckenroth BE, Smith BA, Eberley WA, Heintz NH, Jackman JE, Doublie S. tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc Natl Acad Sci U S A. 2010 Nov 8. PMID:21059936 doi:10.1073/pnas.1010436107

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools