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3pgy
From Proteopedia
m (Protected "3pgy" [edit=sysop:move=sysop]) |
Revision as of 08:18, 8 May 2013
Serine hydroxymethyltransferase from Staphylococcus aureus, S95P mutant.
Function
[GLYA_STAAC] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]
About this Structure
3pgy is a 4 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
Categories: Glycine hydroxymethyltransferase | Staphylococcus aureus | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Joachimiak, A. | Kwon, K. | Makowska-Grzyska, M. | Osipiuk, J. | Center for structural genomics of infectious disease | Csgid | Idp00749 | Serine hydroxymethyltransferase | Structural genomic | Transferase
