This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rnv
From Proteopedia
m (Protected "3rnv" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:3rnv.jpg|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3rnv", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3rnv| PDB=3rnv | SCENE= }} | {{STRUCTURE_3rnv| PDB=3rnv | SCENE= }} | ||
| - | |||
===Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase=== | ===Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/POLG_TUMVJ POLG_TUMVJ]] Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification. Nuclear inclusion protein B: a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity). Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity). Both 6K peptides are indispensable for virus replication (By similarity). Nuclear inclusion protein A: has RNA-binding and proteolytic activities. | ||
==About this Structure== | ==About this Structure== | ||
| Line 17: | Line 10: | ||
[[Category: Turnip mosaic virus]] | [[Category: Turnip mosaic virus]] | ||
[[Category: Ye, K.]] | [[Category: Ye, K.]] | ||
| + | [[Category: Cysteine protease]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Proteolysis]] | ||
Revision as of 07:45, 16 May 2013
Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase
Function
[POLG_TUMVJ] Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification. Nuclear inclusion protein B: a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity). Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity). Both 6K peptides are indispensable for virus replication (By similarity). Nuclear inclusion protein A: has RNA-binding and proteolytic activities.
About this Structure
3rnv is a 1 chain structure with sequence from Turnip mosaic virus. Full crystallographic information is available from OCA.
