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2kzh
From Proteopedia
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{{STRUCTURE_2kzh| PDB=2kzh | SCENE= }} | {{STRUCTURE_2kzh| PDB=2kzh | SCENE= }} | ||
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===Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli=== | ===Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli=== | ||
| + | {{ABSTRACT_PUBMED_21354426}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/TRPC_ECOLI TRPC_ECOLI]] Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021354426</ref><ref group="xtra">PMID:016008567</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021354426</ref><ref group="xtra">PMID:016008567</ref><references group="xtra"/><references/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Phosphoribosylanthranilate isomerase]] | [[Category: Phosphoribosylanthranilate isomerase]] | ||
Revision as of 07:53, 16 May 2013
Contents |
Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli
Template:ABSTRACT PUBMED 21354426
Function
[TRPC_ECOLI] Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
About this Structure
2kzh is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.
Reference
- Setiyaputra S, Mackay JP, Patrick WM. The structure of a truncated phosphoribosylanthranilate isomerase suggests a unified model for evolution of the (betaalpha)8 barrel fold. J Mol Biol. 2011 Apr 29;408(2):291-303. Epub 2011 Feb 25. PMID:21354426 doi:10.1016/j.jmb.2011.02.048
- Patrick WM, Blackburn JM. In vitro selection and characterization of a stable subdomain of phosphoribosylanthranilate isomerase. FEBS J. 2005 Jul;272(14):3684-97. PMID:16008567 doi:10.1111/j.1742-4658.2005.04794.x
