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3tmk
From Proteopedia
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{{STRUCTURE_3tmk| PDB=3tmk | SCENE= }} | {{STRUCTURE_3tmk| PDB=3tmk | SCENE= }} | ||
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===CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION=== | ===CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION=== | ||
| + | {{ABSTRACT_PUBMED_9521686}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/KTHY_YEAST KTHY_YEAST]] Catalyzes the conversion of dTMP to dTDP. | ||
| - | + | ==About this Structure== | |
| - | + | [[3tmk]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TMK OCA]. | |
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| - | == | + | ==See Also== |
| - | + | *[[Thymidylate kinase|Thymidylate kinase]] | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009521686</ref><references group="xtra"/><references/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: DTMP kinase]] | [[Category: DTMP kinase]] | ||
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[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Phosphotransferase]] | [[Category: Phosphotransferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:13:00 2009'' | ||
Revision as of 08:05, 16 May 2013
Contents |
CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION
Template:ABSTRACT PUBMED 9521686
Function
[KTHY_YEAST] Catalyzes the conversion of dTMP to dTDP.
About this Structure
3tmk is a 8 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Lavie A, Konrad M, Brundiers R, Goody RS, Schlichting I, Reinstein J. Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. Biochemistry. 1998 Mar 17;37(11):3677-86. PMID:9521686 doi:10.1021/bi9720787
