2lou
From Proteopedia
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{{STRUCTURE_2lou| PDB=2lou | SCENE= }} | {{STRUCTURE_2lou| PDB=2lou | SCENE= }} | ||
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===AR55 solubilised in DPC micelles=== | ===AR55 solubilised in DPC micelles=== | ||
| + | {{ABSTRACT_PUBMED_23438363}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/APJ_HUMAN APJ_HUMAN]] Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. | ||
==About this Structure== | ==About this Structure== | ||
[[2lou]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOU OCA]. | [[2lou]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOU OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023438363</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Langelaan, D N.]] | [[Category: Langelaan, D N.]] | ||
[[Category: Rainey, J K.]] | [[Category: Rainey, J K.]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
Revision as of 17:59, 19 June 2013
Contents |
AR55 solubilised in DPC micelles
Template:ABSTRACT PUBMED 23438363
Function
[APJ_HUMAN] Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
About this Structure
2lou is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Langelaan DN, Reddy T, Banks AW, Dellaire G, Dupre DJ, Rainey JK. Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking. Biochim Biophys Acta. 2013 Jun;1828(6):1471-83. doi:, 10.1016/j.bbamem.2013.02.005. Epub 2013 Feb 22. PMID:23438363 doi:10.1016/j.bbamem.2013.02.005
