4j4f

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	==Reference==		==Reference==
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	[[Category: Nostoc ellipsosporum]]		[[Category: Nostoc ellipsosporum]]
	[[Category: Gronenborn, A M.]]		[[Category: Gronenborn, A M.]]

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Revision as of 06:40, 20 June 2013

Template:STRUCTURE 4j4f

Contents 1 Structure of P51G Cyanovirin-N swapped tetramer in the P212121 space group 2 Function 3 About this Structure 4 Reference

Structure of P51G Cyanovirin-N swapped tetramer in the P212121 space group

Template:ABSTRACT PUBMED 23610431

Function

[CVN_NOSEL] Mannose-binding lectin.^{[1] [2]}

About this Structure

4j4f is a 4 chain structure with sequence from Nostoc ellipsosporum. Full crystallographic information is available from OCA.

Reference

• Koharudin LM, Liu L, Gronenborn AM. Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates. Proc Natl Acad Sci U S A. 2013 Apr 22. PMID:23610431 doi:10.1073/pnas.1300327110

1. ↑ Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob Agents Chemother. 1997 Jul;41(7):1521-30. PMID:9210678
2. ↑ Botos I, Wlodawer A. Cyanovirin-N: a sugar-binding antiviral protein with a new twist. Cell Mol Life Sci. 2003 Feb;60(2):277-87. PMID:12678493