This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2huw
From Proteopedia
(New page: 200px<br /> <applet load="2huw" size="450" color="white" frame="true" align="right" spinBox="true" caption="2huw, resolution 1.900Å" /> '''X-ray crystal stru...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2huw.gif|left|200px]]<br /> | + | [[Image:2huw.gif|left|200px]]<br /><applet load="2huw" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2huw" size=" | + | |
caption="2huw, resolution 1.900Å" /> | caption="2huw, resolution 1.900Å" /> | ||
'''X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand'''<br /> | '''X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand'''<br /> | ||
| Line 8: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2HUW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with PO4 and YVN as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 2HUW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=YVN:'>YVN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUW OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 13: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Benfield, A | + | [[Category: Benfield, A P.]] |
| - | [[Category: Martin, S | + | [[Category: Martin, S F.]] |
[[Category: PO4]] | [[Category: PO4]] | ||
[[Category: YVN]] | [[Category: YVN]] | ||
| Line 24: | Line 23: | ||
[[Category: sh2]] | [[Category: sh2]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:46:02 2008'' |
Revision as of 15:46, 21 February 2008
|
X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand
Disease
Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]
About this Structure
2HUW is a Single protein structure of sequence from Homo sapiens with and as ligands. Full crystallographic information is available from OCA.
Reference
Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728
Page seeded by OCA on Thu Feb 21 17:46:02 2008
Categories: Homo sapiens | Single protein | Benfield, A P. | Martin, S F. | PO4 | YVN | Contrained | Cylcopropane | Grb2 | Preorganization | Sh2
