4jn4
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4jn4| PDB=4jn4 | SCENE= }} | {{STRUCTURE_4jn4| PDB=4jn4 | SCENE= }} | ||
===Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP=== | ===Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP=== | ||
| + | {{ABSTRACT_PUBMED_23708608}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4jn4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JN4 OCA]. | [[4jn4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JN4 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023708608</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli k-12]] | [[Category: Escherichia coli k-12]] | ||
[[Category: Hendrickson, W A.]] | [[Category: Hendrickson, W A.]] | ||
Revision as of 14:20, 10 July 2013
Contents |
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
Template:ABSTRACT PUBMED 23708608
Function
[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
About this Structure
4jn4 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Qi R, Sarbeng EB, Liu Q, Le KQ, Xu X, Xu H, Yang J, Wong JL, Vorvis C, Hendrickson WA, Zhou L, Liu Q. Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat Struct Mol Biol. 2013 Jul;20(7):900-7. doi: 10.1038/nsmb.2583. Epub 2013 May , 26. PMID:23708608 doi:10.1038/nsmb.2583
