3s8e

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[[Image:3s8e.png|left|200px]]
 
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{{STRUCTURE_3s8e| PDB=3s8e | SCENE= }}
{{STRUCTURE_3s8e| PDB=3s8e | SCENE= }}
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===Phosphorylation regulates assembly of the caspase-6 substrate-binding groove===
===Phosphorylation regulates assembly of the caspase-6 substrate-binding groove===
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{{ABSTRACT_PUBMED_22483120}}
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==Function==
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[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
==About this Structure==
==About this Structure==
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==See Also==
==See Also==
*[[Caspase|Caspase]]
*[[Caspase|Caspase]]
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==Reference==
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<ref group="xtra">PMID:022483120</ref><references group="xtra"/><references/>
[[Category: Caspase-6]]
[[Category: Caspase-6]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 14:29, 10 July 2013

Template:STRUCTURE 3s8e

Contents

Phosphorylation regulates assembly of the caspase-6 substrate-binding groove

Template:ABSTRACT PUBMED 22483120

Function

[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

About this Structure

3s8e is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Velazquez-Delgado EM, Hardy JA. Phosphorylation regulates assembly of the caspase-6 substrate-binding groove. Structure. 2012 Apr 4;20(4):742-51. Epub 2012 Apr 3. PMID:22483120 doi:10.1016/j.str.2012.02.003

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OCA

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