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4bd9

From Proteopedia

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m (Protected "4bd9" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4bd9| PDB=4bd9 | SCENE= }}
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===Structure of the complex between SmCI and human carboxypeptidase A4===
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{{ABSTRACT_PUBMED_23746805}}
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The entry 4bd9 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/CBPA4_HUMAN CBPA4_HUMAN]] Metalloprotease that could be involved in the histone hyperacetylation pathway.<ref>PMID:10383164</ref>
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Authors: Alonso-del-Ribero, M., Reytor, M.L., Trejo, S., Chavez, M.A., Aviles, F.X., Reverter, D.
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==About this Structure==
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[[4bd9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Sabellastarte_magnifica Sabellastarte magnifica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD9 OCA].
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Description: Structure of the complex between SmCI and human carboxypeptidase A4
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==Reference==
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<ref group="xtra">PMID:023746805</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Sabellastarte magnifica]]
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[[Category: Alonso-del-Ribero, M.]]
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[[Category: Aviles, F X.]]
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[[Category: Chavez, M A.]]
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[[Category: Reverter, D.]]
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[[Category: Reytor, M L.]]
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[[Category: Trejo, S A.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine protease inhibitor]]

Revision as of 04:56, 18 July 2013

Template:STRUCTURE 4bd9

Contents

Structure of the complex between SmCI and human carboxypeptidase A4

Template:ABSTRACT PUBMED 23746805

Function

[CBPA4_HUMAN] Metalloprotease that could be involved in the histone hyperacetylation pathway.[1]

About this Structure

4bd9 is a 2 chain structure with sequence from Homo sapiens and Sabellastarte magnifica. Full crystallographic information is available from OCA.

Reference

  • Alonso Del Rivero M, Reytor ML, Trejo SA, Chavez MA, Aviles FX, Reverter D. A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz SmCI in Complex with Human CPA4. Structure. 2013 Jul 2;21(7):1118-26. doi: 10.1016/j.str.2013.04.021. Epub 2013, Jun 6. PMID:23746805 doi:10.1016/j.str.2013.04.021
  1. ↑ Huang H, Reed CP, Zhang JS, Shridhar V, Wang L, Smith DI. Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. Cancer Res. 1999 Jun 15;59(12):2981-8. PMID:10383164

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OCA

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