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3wcy
From Proteopedia
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| - | + | {{STRUCTURE_3wcy| PDB=3wcy | SCENE= }} | |
| + | ===Murine Ifnar1 in complex with interferon-beta=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/INAR1_MOUSE INAR1_MOUSE]] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. [[http://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE]] Has antiviral, antibacterial and anticancer activities. | ||
| - | + | ==About this Structure== | |
| - | + | [[3wcy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCY OCA]. | |
| - | + | [[Category: Mus musculus]] | |
| + | [[Category: Hertzog, P J.]] | ||
| + | [[Category: Rossjohn, J.]] | ||
| + | [[Category: Vivian, J P.]] | ||
| + | [[Category: Weerd, N A.de.]] | ||
| + | [[Category: Cytokine receptor]] | ||
| + | [[Category: Cytokine receptor-cytokine complex]] | ||
| + | [[Category: Fibronectin type iii]] | ||
| + | [[Category: Helical cytokine]] | ||
| + | [[Category: Interferon]] | ||
Revision as of 13:00, 24 July 2013
Murine Ifnar1 in complex with interferon-beta
Function
[INAR1_MOUSE] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. [IFNB_MOUSE] Has antiviral, antibacterial and anticancer activities.
About this Structure
3wcy is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
