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4lsg

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(New page: {{STRUCTURE_4lsg| PDB=4lsg | SCENE= }} ===Structure of Mouse P-Glycoprotein=== ==Function== http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE Energy-dependent efflux pump re...)
m (Protected "4lsg" [edit=sysop:move=sysop])

Revision as of 05:27, 1 August 2013

Template:STRUCTURE 4lsg

Contents

Structure of Mouse P-Glycoprotein

Function

[MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.[1]

About this Structure

4lsg is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. ↑ Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science. 2009 Mar 27;323(5922):1718-22. PMID:19325113 doi:323/5922/1718

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OCA

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