4gfu
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4gfu| PDB=4gfu | SCENE= }} | |
+ | ===PTPN18 in complex with HER2-pY1248 phosphor-peptides=== | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN]] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. | ||
- | + | ==About this Structure== | |
- | + | [[4gfu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFU OCA]. | |
- | + | [[Category: Homo sapiens]] | |
+ | [[Category: Protein-tyrosine-phosphatase]] | ||
+ | [[Category: Du, Y J.]] | ||
+ | [[Category: Sun, J P.]] | ||
+ | [[Category: Wang, H M.]] | ||
+ | [[Category: Yang, D X.]] | ||
+ | [[Category: Yang, F.]] | ||
+ | [[Category: Yu, X.]] | ||
+ | [[Category: Zhang, Y.]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Hydrolase-peptide complex]] | ||
+ | [[Category: Phosphatase]] | ||
+ | [[Category: Tyrosine phosphorylation]] |
Revision as of 21:01, 7 August 2013
PTPN18 in complex with HER2-pY1248 phosphor-peptides
Function
[PTN18_HUMAN] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
About this Structure
4gfu is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.