Thioredoxin Glutathione Reductase
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:2v6o.png|left|200px|thumb|Crystal Structure of Thioredoxin Glutathione Reductase ([[2v6o]])]] | [[Image:2v6o.png|left|200px|thumb|Crystal Structure of Thioredoxin Glutathione Reductase ([[2v6o]])]] | ||
{{STRUCTURE_2x8c| PDB=2x8c | SIZE=400| SCENE= |right|CAPTION=Thioredoxin glutathione reductase with cofactor FAD dimer complex with triethylene glycol [[2x8c]]}} | {{STRUCTURE_2x8c| PDB=2x8c | SIZE=400| SCENE= |right|CAPTION=Thioredoxin glutathione reductase with cofactor FAD dimer complex with triethylene glycol [[2x8c]]}} | ||
| + | |||
Revision as of 10:18, 12 August 2013
Image:2v6o.png
Crystal Structure of Thioredoxin Glutathione Reductase (2v6o)
Thioredoxin Glutathione Reductase (TGR) is an enzyme which bridges two detoxification pathways. It is composed of a small glutaredoxin domain at the N-terminal and a large thioredoxin reductase one at the C-terminal. The images at the left and at the right correspond to one representative TGR, i.e. the crystal structure of Thioredoxin Glutathione Reductase from Schistosoma mansoni (2v6o).
3D Structures of Thioredoxin Glutathione Reductase
2v6o, 2x8c, 2x8g, 2x8h – SmTGR+FAD – Schistosoma mansoni
2x99 - SmTGR+FAD+NADPH
3h4k - SmTGR+FAD+auranofin
