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4lcf

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'''Unreleased structure'''
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{{STRUCTURE_4lcf| PDB=4lcf | SCENE= }}
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===Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex===
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{{ABSTRACT_PUBMED_23914798}}
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The entry 4lcf is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
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Authors: Lee, C.-J., Zhou, P.
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==About this Structure==
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[[4lcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCF OCA].
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Description: Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex
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==Reference==
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<ref group="xtra">PMID:023914798</ref><references group="xtra"/><references/>
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[[Category: Pseudomonas aeruginosa pao1]]
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[[Category: Lee, C J.]]
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[[Category: Zhou, P.]]
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[[Category: Acyl udp-glcnac]]
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[[Category: Baab sandwich]]
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[[Category: Deacetylation]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Hydroxamate]]
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[[Category: Lipid a biosynthesis]]
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[[Category: Lipid a synthesis]]
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[[Category: Lpxc]]

Revision as of 08:22, 21 August 2013

Template:STRUCTURE 4lcf

Contents

Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex

Template:ABSTRACT PUBMED 23914798

Function

[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

About this Structure

4lcf is a 1 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

  • Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure and antibiotic activity of aryl-substituted LpxC inhibitors. J Med Chem. 2013 Aug 5. PMID:23914798 doi:10.1021/jm4007774

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