This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3u59
From Proteopedia
| Line 1: | Line 1: | ||
{{STRUCTURE_3u59| PDB=3u59 | SCENE= }} | {{STRUCTURE_3u59| PDB=3u59 | SCENE= }} | ||
===N-terminal 98-aa fragment of smooth muscle tropomyosin beta=== | ===N-terminal 98-aa fragment of smooth muscle tropomyosin beta=== | ||
| - | {{ | + | {{ABSTRACT_PUBMED_22119916}} |
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/TPM2_CHICK TPM2_CHICK]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. | ||
==About this Structure== | ==About this Structure== | ||
| Line 8: | Line 11: | ||
==See Also== | ==See Also== | ||
*[[Tropomyosin|Tropomyosin]] | *[[Tropomyosin|Tropomyosin]] | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022119916</ref><references group="xtra"/><references/> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Dominguez, R.]] | [[Category: Dominguez, R.]] | ||
Revision as of 09:01, 4 September 2013
Contents |
N-terminal 98-aa fragment of smooth muscle tropomyosin beta
Template:ABSTRACT PUBMED 22119916
Function
[TPM2_CHICK] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
About this Structure
3u59 is a 4 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Rao JN, Rivera-Santiago R, Li XE, Lehman W, Dominguez R. Structural analysis of smooth muscle tropomyosin alpha and beta isoforms. J Biol Chem. 2012 Jan 27;287(5):3165-74. Epub 2011 Nov 27. PMID:22119916 doi:10.1074/jbc.M111.307330
