This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3vww

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_3vww| PDB=3vww | SCENE= }}
 +
===Crystal structure of a0-domain of P5 from H. sapiens===
 +
{{ABSTRACT_PUBMED_23949117}}
-
The entry 3vww is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/PDIA6_HUMAN PDIA6_HUMAN]] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.<ref>PMID:15466936</ref> <ref>PMID:12204115</ref>
-
Authors: Inaba, K., Suzuki, M.
+
==About this Structure==
 +
[[3vww]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VWW OCA].
-
Description: Crystal structure of a0-domain of P5 from H. sapiens
+
==Reference==
 +
<ref group="xtra">PMID:023949117</ref><references group="xtra"/><references/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Protein disulfide-isomerase]]
 +
[[Category: Inaba, K.]]
 +
[[Category: Suzuki, M.]]
 +
[[Category: Isomerase]]
 +
[[Category: Pdi family member]]
 +
[[Category: Protein disulfide isomerase]]
 +
[[Category: Thioredoxin fold]]

Revision as of 10:41, 4 September 2013

Template:STRUCTURE 3vww

Contents

Crystal structure of a0-domain of P5 from H. sapiens

Template:ABSTRACT PUBMED 23949117

Function

[PDIA6_HUMAN] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.[1] [2]

About this Structure

3vww is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sato Y, Kojima R, Okumura M, Hagiwara M, Masui S, Maegawa K, Saiki M, Horibe T, Suzuki M, Inaba K. Synergistic cooperation of PDI family members in peroxiredoxin 4-driven oxidative protein folding. Sci Rep. 2013 Aug 16;3:2456. doi: 10.1038/srep02456. PMID:23949117 doi:10.1038/srep02456
  1. ↑ Jordan PA, Stevens JM, Hubbard GP, Barrett NE, Sage T, Authi KS, Gibbins JM. A role for the thiol isomerase protein ERP5 in platelet function. Blood. 2005 Feb 15;105(4):1500-7. Epub 2004 Oct 5. PMID:15466936 doi:10.1182/blood-2004-02-0608
  2. ↑ Kikuchi M, Doi E, Tsujimoto I, Horibe T, Tsujimoto Y. Functional analysis of human P5, a protein disulfide isomerase homologue. J Biochem. 2002 Sep;132(3):451-5. PMID:12204115

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3vww"
Personal tools