1nez
From Proteopedia
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| - | [[Image:1nez.png|left|200px]] | ||
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{{STRUCTURE_1nez| PDB=1nez | SCENE= }} | {{STRUCTURE_1nez| PDB=1nez | SCENE= }} | ||
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===The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity=== | ===The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity=== | ||
| + | {{ABSTRACT_PUBMED_12594948}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/HA1T_MOUSE HA1T_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/CD8A_MOUSE CD8A_MOUSE]] Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | ||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Beta-2 microglobulin|Beta-2 microglobulin]] | *[[Beta-2 microglobulin|Beta-2 microglobulin]] | ||
| + | *[[CD8|CD8]] | ||
*[[Major histocompatibility complex|Major histocompatibility complex]] | *[[Major histocompatibility complex|Major histocompatibility complex]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012594948</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012594948</ref><references group="xtra"/><references/> |
[[Category: Cheroutre, H.]] | [[Category: Cheroutre, H.]] | ||
[[Category: Joachimiak, A.]] | [[Category: Joachimiak, A.]] | ||
Revision as of 03:01, 20 September 2013
Contents |
The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity
Template:ABSTRACT PUBMED 12594948
Function
[HA1T_MOUSE] Involved in the presentation of foreign antigens to the immune system. [CD8A_MOUSE] Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. [B2MG_MOUSE] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
About this Structure
1nez is a 4 chain structure. Full crystallographic information is available from OCA.
See Also
Reference
- Liu Y, Xiong Y, Naidenko OV, Liu JH, Zhang R, Joachimiak A, Kronenberg M, Cheroutre H, Reinherz EL, Wang JH. The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory. Immunity. 2003 Feb;18(2):205-15. PMID:12594948
