4hwt

From Proteopedia

proteopedia linkproteopedia link

Revision as of 07:01, 2 May 2013 (edit) OCA (Talk | contribs) ← Previous diff		Revision as of 04:07, 20 September 2013 (edit) (undo) OCA (Talk | contribs) Next diff →
Line 1:		Line 1:
-	'''Unreleased structure'''	+	{{STRUCTURE_4hwt| PDB=4hwt | SCENE= }}
		+	===Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor===
		+	{{ABSTRACT_PUBMED_23362938}}
-	The entry 4hwt is ON HOLD until Paper Publication	+	==About this Structure==
		+	[[4hwt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HWT OCA].
-	Authors: Hilgers, M.T.	+	==Reference==
-		+	<ref group="xtra">PMID:023362938</ref><references group="xtra"/><references/>
-	Description: Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor	+	[[Category: Homo sapiens]]
		+	[[Category: Threonine--tRNA ligase]]
		+	[[Category: Hilgers, M T.]]
		+	[[Category: Aminoacyl-trna synthetase]]
		+	[[Category: Ligase-ligase inhibitor complex]]
		+	[[Category: Protein-inhibitor complex]]

---

Revision as of 04:07, 20 September 2013

Template:STRUCTURE 4hwt

Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor

Template:ABSTRACT PUBMED 23362938

About this Structure

4hwt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Teng M, Hilgers MT, Cunningham ML, Borchardt A, Locke JB, Abraham S, Haley G, Kwan BP, Hall C, Hough GW, Shaw KJ, Finn J. Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J Med Chem. 2013 Feb 28;56(4):1748-60. doi: 10.1021/jm301756m. Epub 2013 Feb 12. PMID:23362938 doi:10.1021/jm301756m