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4j0l

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4j0l| PDB=4j0l | SCENE= }}
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===Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules===
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{{ABSTRACT_PUBMED_23871710}}
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The entry 4j0l is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/CHIC_SECCE CHIC_SECCE]] Defense against chitin containing fungal pathogens. Binds the hyphal tips of fungi and degrades nascent chitin.<ref>PMID:11999399</ref> <ref>PMID:11826968</ref> <ref>PMID:12092848</ref>
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Authors: Umemoto, N., Numata, T., Ohnuma, T., Fukamizo, T.
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==About this Structure==
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[[4j0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J0L OCA].
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Description: Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules
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==Reference==
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<ref group="xtra">PMID:023871710</ref><references group="xtra"/><references/>
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[[Category: Chitinase]]
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[[Category: Secale cereale]]
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[[Category: Fukamizo, T.]]
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[[Category: Numata, T.]]
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[[Category: Ohnuma, T.]]
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[[Category: Umemoto, N.]]
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[[Category: Carbohydrate]]
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[[Category: Chitinase]]
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[[Category: Hydrolase]]

Revision as of 07:59, 16 October 2013

Template:STRUCTURE 4j0l

Contents

Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules

Template:ABSTRACT PUBMED 23871710

Function

[CHIC_SECCE] Defense against chitin containing fungal pathogens. Binds the hyphal tips of fungi and degrades nascent chitin.[1] [2] [3]

About this Structure

4j0l is a 1 chain structure with sequence from Secale cereale. Full crystallographic information is available from OCA.

Reference

  • Ohnuma T, Umemoto N, Kondo K, Numata T, Fukamizo T. Complete subsite mapping of a "loopful" GH19 chitinase from rye seeds based on its crystal structure. FEBS Lett. 2013 Aug 19;587(16):2691-7. doi: 10.1016/j.febslet.2013.07.008. Epub, 2013 Jul 18. PMID:23871710 doi:http://dx.doi.org/10.1016/j.febslet.2013.07.008
  1. ↑ Ohnuma T, Yagi M, Yamagami T, Taira T, Aso Y, Ishiguro M. Molecular cloning, functional expression, and mutagenesis of cDNA encoding rye (Secale cereale) seed chitinase-c. Biosci Biotechnol Biochem. 2002 Feb;66(2):277-84. PMID:11999399
  2. ↑ Taira T, Yamagami T, Aso Y, Ishiguro M, Ishihara M. Localization, accumulation, and antifungal activity of chitinases in rye (Secale cereale) seed. Biosci Biotechnol Biochem. 2001 Dec;65(12):2710-8. PMID:11826968
  3. ↑ Taira T, Ohnuma T, Yamagami T, Aso Y, Ishiguro M, Ishihara M. Antifungal activity of rye (Secale cereale) seed chitinases: the different binding manner of class I and class II chitinases to the fungal cell walls. Biosci Biotechnol Biochem. 2002 May;66(5):970-7. PMID:12092848

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