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2m6g

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'''Unreleased structure'''
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{{STRUCTURE_2m6g| PDB=2m6g | SCENE= }}
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===Solution structure of cis(C2-P3) trans (D5-P6) form of lO959 in water===
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{{ABSTRACT_PUBMED_24115170}}
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The entry 2m6g is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/COW_CONLO COW_CONLO]] Activates high voltage-activated calcium channels (Cav). This activity is in contrast to other contryphans that inhibit high voltage-gated calcium channels.
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Authors: Sonti, R.
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==About this Structure==
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[[2m6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M6G OCA].
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Description: Solution structure of cis(C2-P3) trans (D5-P6) form of lO959 in water
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==Reference==
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<ref group="xtra">PMID:024115170</ref><references group="xtra"/><references/>
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[[Category: Sonti, R.]]
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[[Category: Lo959]]
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[[Category: Toxin]]
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[[Category: Water]]

Revision as of 09:43, 30 October 2013

Template:STRUCTURE 2m6g

Contents

Solution structure of cis(C2-P3) trans (D5-P6) form of lO959 in water

Template:ABSTRACT PUBMED 24115170

Function

[COW_CONLO] Activates high voltage-activated calcium channels (Cav). This activity is in contrast to other contryphans that inhibit high voltage-gated calcium channels.

About this Structure

2m6g is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Sonti R, Gowd KH, Rao KN, Ragothama S, Rodriguez A, Perez JJ, Balaram P. Conformational Diversity in Contryphans from Conus Venom: cis-trans Isomerisation and Aromatic/Proline Interactions in the 23-Membered Ring of a 7-Residue Peptide Disulfide Loop. Chemistry. 2013 Nov 4;19(45):15175-89. doi: 10.1002/chem.201301722. Epub 2013 Sep, 23. PMID:24115170 doi:http://dx.doi.org/10.1002/chem.201301722

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