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4lv7

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'''Unreleased structure'''
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{{STRUCTURE_4lv7| PDB=4lv7 | SCENE= }}
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===Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase E82C/S142C===
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The entry 4lv7 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/IPPK_ARATH IPPK_ARATH]] Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). Phytate is a regulator of intracellular signaling, a highly abundant animal antinutrient, and a phosphate store in plant seeds. Also phosphorylates Ins(1,3,4,6)P4 and Ins(1,4,5,6)P4 to produce Ins(1,2,3,4,6)P5 and Ins(1,2,4,5,6)P5.<ref>PMID:16107538</ref> <ref>PMID:16223361</ref>
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Authors: Gosein, V., Miller, G.J.
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==About this Structure==
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[[4lv7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LV7 OCA].
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Description: Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase E82C/S142C
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Arabidopsis thaliana]]
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[[Category: Inositol-pentakisphosphate 2-kinase]]
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[[Category: Gosein, V.]]
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[[Category: Miller, G J.]]
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[[Category: Atipk1]]
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[[Category: Inositol phosphorylation]]
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[[Category: Ins5p 2-k]]
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[[Category: Ip5 2-k]]
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[[Category: Ipk]]
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[[Category: Transferase]]

Revision as of 07:51, 6 November 2013

Template:STRUCTURE 4lv7

Contents

Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase E82C/S142C

Function

[IPPK_ARATH] Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). Phytate is a regulator of intracellular signaling, a highly abundant animal antinutrient, and a phosphate store in plant seeds. Also phosphorylates Ins(1,3,4,6)P4 and Ins(1,4,5,6)P4 to produce Ins(1,2,3,4,6)P5 and Ins(1,2,4,5,6)P5.[1] [2]

About this Structure

4lv7 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

  1. ↑ Stevenson-Paulik J, Bastidas RJ, Chiou ST, Frye RA, York JD. Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12612-7. Epub 2005 Aug 17. PMID:16107538 doi:10.1073/pnas.0504172102
  2. ↑ Sweetman D, Johnson S, Caddick SE, Hanke DE, Brearley CA. Characterization of an Arabidopsis inositol 1,3,4,5,6-pentakisphosphate 2-kinase (AtIPK1). Biochem J. 2006 Feb 15;394(Pt 1):95-103. PMID:16223361 doi:BJ20051331

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