4jwc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4jwc| PDB=4jwc | SCENE= }}
 +
===Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16)===
 +
{{ABSTRACT_PUBMED_24164259}}
-
The entry 4jwc is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [[http://www.uniprot.org/uniprot/CTHL3_BOVIN CTHL3_BOVIN]] Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.
-
Authors: Zahn, M., Straeter, N.
+
==About this Structure==
 +
[[4jwc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JWC OCA].
-
Description: Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16)
+
==Reference==
 +
<ref group="xtra">PMID:024164259</ref><references group="xtra"/><references/>
 +
[[Category: Straeter, N.]]
 +
[[Category: Zahn, M.]]
 +
[[Category: Antimicrobial peptide]]
 +
[[Category: Chaperone]]
 +
[[Category: Chaperone-antibiotic complex]]
 +
[[Category: Chaperone-protein binding complex]]
 +
[[Category: Peptide binding]]
 +
[[Category: Peptide binding protein]]

Revision as of 08:16, 13 November 2013

Template:STRUCTURE 4jwc

Contents

Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16)

Template:ABSTRACT PUBMED 24164259

Function

[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [CTHL3_BOVIN] Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.

About this Structure

4jwc is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Zahn M, Kieslich B, Berthold N, Knappe D, Hoffmann R, Strater N. Structural Identification of DnaK Binding Sites Within Bovine and Sheep Bactenecin Bac7. Protein Pept Lett. 2013 Oct 25. PMID:24164259

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4jwc"
Personal tools