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2m5i

From Proteopedia

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m (Protected "2m5i" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_2m5i| PDB=2m5i | SCENE= }}
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===NMR structures of human apoptotic protein tBid in LPPG micelle===
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{{ABSTRACT_PUBMED_24158446}}
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The entry 2m5i is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/BID_HUMAN BID_HUMAN]] The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.<ref>PMID:14583606</ref>
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Authors: Wang, Y., Suzuki, M., Tjandra, N.
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==About this Structure==
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[[2m5i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5I OCA].
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Description: NMR structures of human apoptotic protein tBid in LPPG micelle
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==Reference==
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<ref group="xtra">PMID:024158446</ref><references group="xtra"/><references/>
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[[Category: Tjandra, N.]]
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[[Category: Wang, Y.]]
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[[Category: Apoptosis]]
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[[Category: Lppg micelle]]
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[[Category: Membrane protein]]
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[[Category: Tbid]]

Revision as of 08:21, 13 November 2013

Template:STRUCTURE 2m5i

Contents

NMR structures of human apoptotic protein tBid in LPPG micelle

Template:ABSTRACT PUBMED 24158446

Function

[BID_HUMAN] The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.[1]

About this Structure

2m5i is a 1 chain structure. Full experimental information is available from OCA.

Reference

  1. ↑ Renshaw SA, Dempsey CE, Barnes FA, Bagstaff SM, Dower SK, Bingle CD, Whyte MK. Three novel Bid proteins generated by alternative splicing of the human Bid gene. J Biol Chem. 2004 Jan 23;279(4):2846-55. Epub 2003 Oct 28. PMID:14583606 doi:http://dx.doi.org/10.1074/jbc.M309769200

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OCA

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