This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1h35
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:1h35.png|left|200px]] | ||
| - | |||
{{STRUCTURE_1h35| PDB=1h35 | SCENE= }} | {{STRUCTURE_1h35| PDB=1h35 | SCENE= }} | ||
| - | + | ===Structures of human oxidosqualene cyclase inhibitors bound to a homolgous enzyme=== | |
| - | === | + | |
| - | + | ||
{{ABSTRACT_PUBMED_12747780}} | {{ABSTRACT_PUBMED_12747780}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1h35]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[1h35]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H35 OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012747780</ref>< | + | <ref group="xtra">PMID:012747780</ref><references group="xtra"/><references/> |
| - | [[Category: | + | [[Category: Atcc 27009]] |
| + | [[Category: Squalene--hopene cyclase]] | ||
[[Category: Aebi, J D.]] | [[Category: Aebi, J D.]] | ||
[[Category: Dehmlow, H.]] | [[Category: Dehmlow, H.]] | ||
| Line 22: | Line 19: | ||
[[Category: Cholesterol biosynthesis]] | [[Category: Cholesterol biosynthesis]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
| - | [[Category: Interaction]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
| - | [[Category: Monotopic membrane | + | [[Category: Monotopic membrane protein]] |
| - | + | ||
Revision as of 12:16, 20 November 2013
Structures of human oxidosqualene cyclase inhibitors bound to a homolgous enzyme
Template:ABSTRACT PUBMED 12747780
About this Structure
1h35 is a 3 chain structure with sequence from Atcc 27009. Full crystallographic information is available from OCA.
Reference
- Lenhart A, Reinert DJ, Aebi JD, Dehmlow H, Morand OH, Schulz GE. Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. J Med Chem. 2003 May 22;46(11):2083-92. PMID:12747780 doi:http://dx.doi.org/10.1021/jm0211218
