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2xqq
From Proteopedia
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{{STRUCTURE_2xqq| PDB=2xqq | SCENE= }} | {{STRUCTURE_2xqq| PDB=2xqq | SCENE= }} | ||
| + | ===Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide (Ac-SRGTQTE).=== | ||
| + | {{ABSTRACT_PUBMED_21533121}} | ||
| - | == | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/DYL2_HUMAN DYL2_HUMAN]] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). | |
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==About this Structure== | ==About this Structure== | ||
| - | [[2xqq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2xqq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQQ OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021533121</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021533121</ref><references group="xtra"/><references/> |
| - | [[Category: | + | [[Category: Human]] |
[[Category: Harmat, V.]] | [[Category: Harmat, V.]] | ||
[[Category: Hetenyi, C.]] | [[Category: Hetenyi, C.]] | ||
Revision as of 12:21, 20 November 2013
Contents |
Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide (Ac-SRGTQTE).
Template:ABSTRACT PUBMED 21533121
Function
[DYL2_HUMAN] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).
About this Structure
2xqq is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Rapali P, Radnai L, Suveges D, Harmat V, Tolgyesi F, Wahlgren WY, Katona G, Nyitray L, Pal G. Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. PLoS One. 2011 Apr 18;6(4):e18818. PMID:21533121 doi:10.1371/journal.pone.0018818
