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4l87

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==About this Structure==
==About this Structure==
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[[4l87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L87 OCA].
+
[[4l87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L87 OCA].
==Reference==
==Reference==
<ref group="xtra">PMID:024095058</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024095058</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Serine--tRNA ligase]]
[[Category: Serine--tRNA ligase]]
[[Category: Xu, X.]]
[[Category: Xu, X.]]

Revision as of 08:29, 27 November 2013

Template:STRUCTURE 4l87

Contents

Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution

Template:ABSTRACT PUBMED 24095058

Function

[SYSC_HUMAN] Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).[1]

About this Structure

4l87 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Xu X, Shi Y, Yang XL. Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes. Structure. 2013 Oct 1. pii: S0969-2126(13)00342-0. doi:, 10.1016/j.str.2013.08.021. PMID:24095058 doi:http://dx.doi.org/10.1016/j.str.2013.08.021
  1. ↑ Vincent C, Tarbouriech N, Hartlein M. Genomic organization, cDNA sequence, bacterial expression, and purification of human seryl-tRNA synthase. Eur J Biochem. 1997 Nov 15;250(1):77-84. PMID:9431993

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