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4i1n

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4i1n| PDB=4i1n | SCENE= }}
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===R104A-ca1697 nanobody binding to the binary DHFR.folate complex===
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The entry 4i1n is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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Authors: Oyen, D., Steyaert, J., Barlow, J.N.
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==About this Structure==
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[[4i1n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I1N OCA].
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Description: R104A-ca1697 nanobody binding to the binary DHFR.folate complex
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[[Category: Dihydrofolate reductase]]
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[[Category: Barlow, J N.]]
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[[Category: Oyen, D.]]
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[[Category: Steyaert, J.]]
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[[Category: Alpha/beta fold]]
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[[Category: Folate derivative]]
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[[Category: Hydride transfer]]
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[[Category: Immunoglobulin fold]]
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[[Category: Nadph]]
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[[Category: Oxidoreductase-immune system complex]]
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[[Category: Reductase]]

Revision as of 10:30, 27 November 2013

Template:STRUCTURE 4i1n

R104A-ca1697 nanobody binding to the binary DHFR.folate complex

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4i1n is a 2 chain structure. Full crystallographic information is available from OCA.

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OCA

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