Stromal Derived Factor 1

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[[Image:2kec.jpg|left|thumb|300px|NMR Structure of the Stromal Derived Factor 1α, [[2kec]]]]
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[[Image:2kec.jpg|left|thumb|300px|NMR Structure of the Stromal cell-derived factor 1α, [[2kec]]]]
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{{STRUCTURE_2kec| right| PDB=2kec | SCENE= |CAPTION=Stromal Derived Factor 1α, [[2kec]] }}
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{{STRUCTURE_1qg7|right| PDB=1qg7 | SCENE= |CAPTION=Stromal cell-derived factor 1α dimer complex with sulfate, [[1qg7]] }}
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[[Stromal Derived Factor 1]] (SDF-1α) or CXCL12 is a small cytokine from the chemokine family. It is natural ligand of [[CXC chemokine receptor type 4|CXCR4]] It has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis. The images on the left and right correspond to one representative SDF-1α structure, ''i.e.'' the human SDF-1α ([[2kec]]).
[[Stromal Derived Factor 1]] (SDF-1α) or CXCL12 is a small cytokine from the chemokine family. It is natural ligand of [[CXC chemokine receptor type 4|CXCR4]] It has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis. The images on the left and right correspond to one representative SDF-1α structure, ''i.e.'' the human SDF-1α ([[2kec]]).
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== 3D Structures of Stromal Derived Factor 1 ==
== 3D Structures of Stromal Derived Factor 1 ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[2kec]], [[2ked]], [[2kee]], [[2sdf]], [[1sdf]] - hSDF1α – NMR - human<br />
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[[2kec]], [[2ked]], [[2kee]], [[2sdf]], [[1sdf]], [[1vmc]] - hSDF1α – NMR - human<br />
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[[2k0l]], [[2k01]] – hSDF1α (mutant) – NMR<br />
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[[1qg7]], [[3hp3]] - hSDF1α<br />
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[[1a15]] - hSDF1α (mutant)<br />
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[[2k0l]], [[2k01]], [[2kol]] – hSDF1α (mutant) – NMR<br />
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[[1a15]], [[3gv3]] - hSDF1α (mutant)<br />
[[2nwg]] - hSDF1α+heparin<br />
[[2nwg]] - hSDF1α+heparin<br />
[[2j7z]] - hSDF1α residues 22-89<br />
[[2j7z]] - hSDF1α residues 22-89<br />

Current revision

NMR Structure of the Stromal cell-derived factor 1α, 2kec
NMR Structure of the Stromal cell-derived factor 1α, 2kec

PDB ID 1qg7

Drag the structure with the mouse to rotate
Stromal cell-derived factor 1α dimer complex with sulfate, 1qg7
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml
















Stromal Derived Factor 1 (SDF-1α) or CXCL12 is a small cytokine from the chemokine family. It is natural ligand of CXCR4 It has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis. The images on the left and right correspond to one representative SDF-1α structure, i.e. the human SDF-1α (2kec).







3D Structures of Stromal Derived Factor 1

Updated on 19-December-2013

2kec, 2ked, 2kee, 2sdf, 1sdf, 1vmc - hSDF1α – NMR - human
1qg7, 3hp3 - hSDF1α
2k0l, 2k01, 2kol – hSDF1α (mutant) – NMR
1a15, 3gv3 - hSDF1α (mutant)
2nwg - hSDF1α+heparin
2j7z - hSDF1α residues 22-89
2k03, 2k04, 2k05 - hSDF1α (mutant)+ hCXCR4 N-terminal (mutant)

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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