2mf8
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | [[2mf8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2mf8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MF8 OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024097990</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024097990</ref><references group="xtra"/><references/> | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Connell, M R.O.]] | [[Category: Connell, M R.O.]] | ||
[[Category: Cubeddu, L.]] | [[Category: Cubeddu, L.]] | ||
Revision as of 08:56, 25 December 2013
Contents |
HADDOCK model of MyT1 F4F5 - DNA complex
Template:ABSTRACT PUBMED 24097990
Function
[MYT1_MOUSE] Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription (By similarity).[1]
About this Structure
2mf8 is a 3 chain structure with sequence from Lk3 transgenic mice. Full experimental information is available from OCA.
Reference
- Gamsjaeger R, O'Connell MR, Cubeddu L, Shepherd NE, Lowry JA, Kwan AH, Vandevenne M, Swanton MK, Matthews JM, Mackay JP. A structural analysis of DNA binding by Myelin Transcription Factor 1 double zinc fingers. J Biol Chem. 2013 Oct 6. PMID:24097990 doi:http://dx.doi.org/10.1074/jbc.M113.482075
- ↑ Kim JG, Armstrong RC, v Agoston D, Robinsky A, Wiese C, Nagle J, Hudson LD. Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. J Neurosci Res. 1997 Oct 15;50(2):272-90. PMID:9373037
